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Cinema Politica is committed to supporting alternative, independent, and radical political film and video, and the artists who dare to devote time, passion and resources to telling stories from the margins. We program works that feature under-represented subjects and tell stories which confront and challenge conventional fiction and documentary narratives.
Maximum Tolerated Dose
Directed by Karol Orzechowski ∙ 2012 ∙ Canada
An animal / human experiment to find the highest dose of a chemical that, when administered to a group of test subjects in a clinical trial, does not result in a fatality due to short-term toxicity. This dose is then used for longer-term safety studies of the same species, lasting anywhere from two years to a lifetime. The MTD test is controversial, however, in part because of difficulties in extrapolating findings to more realistic doses, and in extrapolating results from animals to humans.